Shubhashis Saha, MD

Shubhashis Saha, MD

Internal Medicine Resident · Cardiovascular Medicine & Outcomes Research

Internal medicine resident at Cook County Health (John H. Stroger Jr. Hospital) and MSc in Clinical Investigation candidate at Northwestern University. My clinical and research work centers on cardiovascular medicine — heart failure, structural and nuclear cardiology, and large-scale outcomes research — building toward a career as an academic cardiologist.

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Portrait of Dr. Shubhashis Saha
SS
8
Peer-reviewed journal articles
25
National & international abstracts
16
First-author works
5
Cardiology societies presented — ACC (×2) · AHA (×2) · ASNC (×2) · SCAI · HRS

Education & Training

Current appointments and degrees

Internal Medicine Residency
Cook County Health · John H. Stroger Jr. Hospital, Chicago, IL
2024 – 2027
High-volume urban safety-net program. Program Director: Anshu Singh, MD. Early and repeated dedicated cardiology training across CCU, cardiology floors, consults, and clinics.
MSc in Clinical Investigation (MSCI)
Northwestern University, Chicago/Evanston, IL
2025 – 2027
Formal graduate training in clinical research methods — epidemiology, biostatistics (basic & advanced), clinical trials, EHR methods, and research ethics — with a mentored cardiovascular research thesis; will graduate alongside residency.
M.B.B.S. (MD-equivalent)
Christian Medical College, Vellore, India
2015 – 2021
Very high-volume quaternary referral and teaching hospital, renowned for serving the underserved. Followed by compulsory service including a year in the cardiothoracic surgery ICU.

Cardiovascular Clinical Experience

6 months of dedicated cardiology primary service completed; 2 further months planned in PGY-3

Coronary Care Unit (CCU) & Cardiology Floors
Cook County Health, Chicago, IL
2025 – present
  • CCU: post-STEMI care, symptomatic bradycardia requiring temporary pacemaker placement, cardiogenic shock requiring mechanical circulatory support, and VT storm managed with multiple antiarrhythmics.
  • Cardiology floors: high-volume acute decompensated heart failure, pulmonary embolism, and antiarrhythmic initiation.
  • Completed 6 months on a dedicated cardiology primary service — consults, CCU, cardiology floors, and cardiology clinics — across the PGY-1 and PGY-2 years, with 2 further months planned in PGY-3.
Inpatient Consults & Outpatient Cardiology Clinics
Cook County Health, Chicago, IL
2024 – present
Evaluation of syncope, heart failure, chest pain, arrhythmias, and cardiac device issues; ED STEMI activations and impending cardiogenic shock. Longitudinal outpatient experience in general cardiology, electrophysiology, and structural clinics.
Observership — Adult & Pediatric Cardiology
Christian Medical College, Vellore, India
April 2024
Completed between residency match results and the start of residency.
  • Spent most mornings in the catheterization laboratory observing routine diagnostic catheterizations, aortic aneurysm repair, complex peripheral artery disease interventions, congenital heart disease repairs including VSD and ASD closure, electrophysiology studies, pacemaker placement, and atrial fibrillation ablation.
  • Participated in rounds through the afternoons and evenings, assisting with cardiology ICU and floor patient management.
Cardiothoracic Surgery ICU
Christian Medical College, Vellore, India
2022 – 2023
  • Capacity: independently managed patients under the supervision of cardiac anesthesiologists and cardiac surgeons.
  • Case mix: adults (95%) and children (5%); 95% post-operative and 5% pre-operative — including aortic dissection requiring blood-pressure stabilization and NSTEMI.
  • Bedside echocardiography: obtaining standard windows, identifying pericardial effusion, visual estimation of ejection fraction, and recognizing wall-motion abnormalities.
  • ECG interpretation: cardiac arrhythmias, conduction blocks, and signs of digoxin toxicity.
  • Academics: attended the weekly academic half-days intended for cardiology fellows.
  • Earlier, served as first assistant on a CABG during a medical student elective at Uppsala University, Sweden.

Research & Scholarship

Cardiovascular outcomes research, meta-analyses, and case work. First author Most meaningful Published Accepted Under review

Peer-reviewed journal articles

Hospital-level variations in outcomes and readmissions among patients with STEMI and cardiogenic shock receiving mechanical circulatory support: insights from a national cohort. Accepted
Murthi M, Quevedo A, Saha S, Memdani A, Baskaran N, Vij A. Catheterization and Cardiovascular Interventions. 2026.
Performance of simple outpatient-based biomarker panels for screening of steatotic liver disease in women with morbid obesity from Southern India. FirstPublished
Saha S, Dass S, Cherian KE, Jiwanmall SA, Kattula D, Reddy S, Jaleel R, Paul TV, Kapoor N. touchREVIEWS in Endocrinology. 2025;21(1):48–54. PMID 40485655.
An unusual association of idiopathic syndrome of inappropriate antidiuretic hormone secretion (SIADH) with interstitial lung disease. FirstPublished
Saha S, Saha T, Sharma S, Mahmood N. Cureus. 2023;15(11):e48304. PMID 37942124.
Screening practices for breast and cervical cancer and associated factors among rural women in Vellore, Tamil Nadu. FirstPublished
Saha S, Priya SM, Surender A, et al. Indian Journal of Cancer. 2022;60(1):65–71. PMID 35017369.
Placenta percreta presenting as uterine rupture following previous B-Lynch suture. FirstPublished
Saha S, Abraham A, Raja Navaneethan P, Abraham K. BMJ Case Reports. 2021;14(10):e245593. PMID 34598970.
Vascular consequences: a case report on posterior circulation infarction as a sequela of COVID-19. Published
Philip AM, George LJ, Saha S, Sadanandan S. Cureus. 2024;16(7):e65837. PMID 39219954.
Barriers and facilitators for the use of telehealth by healthcare providers in India — a systematic review. Published
Sharma P, Rao S, Krishna Kumar P, Nair AR, Agrawal D, Zadey S, Surendran G, Joseph RG, Dayma G, Rafeekh L, Saha S, et al. PLOS Digital Health. 2024;3(12):e0000398. PMID 39642108.
A retrospective study on the clinical profile of patients with firecracker-related injury presenting to the emergency department of a tertiary care center in South India. Published
Sethy A, Saha S, Hazra D, Abhilash KPP. Current Medical Issues. 2020;18(1):1–6.

Book chapter (peer-reviewed)

Delayed Sleep-Wake Phase Disorder (DSWPD). First
Saha S, Triantafillou T. In: The 5-Minute Clinical Consult 2027. Wolters Kluwer; 2027:812–814.

Manuscripts under review

Structural outcomes among patients receiving targeted therapy for ATTR cardiac amyloidosis — a systematic review and meta-analysis. Most meaningfulUnder review
Varma R, Saha S, Nandyal S, Ilelaboye A, Vinjamuri S, Vij A, Malhotra S. JACC: Heart Failure.
Biventricular Takotsubo syndrome following sunitinib initiation: a case report. FirstMost meaningfulUnder review
Saha S, Shrestha P, Sabanci R, Gomez J. JACC: Case Reports.
A 65-year-old man with severe thrombocytopenia during an ulcerative colitis flare. FirstMost meaningfulUnder review
Jha A, Saha S, Kazintet Y, Thakur A, Rohr L. NEJM Evidence.
Scorpion envenomation presenting to the adult emergency department in Southern India. FirstUnder review
Saha S, Singh B, Speedie A, Liz S, Abhilash KPP. Medical Journal of Dr. D.Y. Patil Vidyapeeth.
National & international conference abstracts — first author (8)
National trends, outcomes, and resource utilization in AMI-related hospitalizations among adults with type 1 diabetes — National Inpatient Sample study (2016–2023). FirstOutstanding Abstract Award
Saha S, et al. Oral and poster presentation, ENDO 2026 (Endocrine Society Annual Meeting).
Prognostic impact of PET-diagnosed coronary microvascular disease on MACE outcomes: a systematic review and meta-analysis. First
Saha S, Philip AM, George LJ, John K, Nayar J, Caputi A, Malhotra S. J Nucl Cardiol (ASNC 2025). 2025;50(Suppl):102423.
Beyond statins in acute coronary syndrome — an updated meta-analysis on PCSK9 inhibitors and their impact on lipid control, plaque burden, and clinical outcomes. First
Saha S, Singla A, Sodhi SS, et al. J Am Coll Cardiol (ACC 2026). 2026;87(13 Suppl):A225.
Improvement in measures of quality of life among patients receiving targeted therapy for ATTR amyloidosis: a meta-analysis of randomized controlled trials. First
Saha S, Vij A, Nandyal S, Varma R, Kanitsoraphan C, Malhotra S. J Am Coll Cardiol (ACC 2025). 2025;85(12 Suppl):1727.
Lack of improvement in cardiac function among patients receiving targeted therapy for ATTR amyloidosis: a meta-analysis of randomized controlled trials. First
Saha S, Vij A, Varma R, Nandyal S, Kanitsoraphan C, Malhotra S. J Am Coll Cardiol (ACC 2025). 2025;85(12 Suppl):1726.
Transcatheter device closure of ventricular septal defect in children weighing less than 30 lbs is a safe and effective procedure: 10-year experience from a single tertiary center in Southern India. First
Saha S, Mandal A, George OK. Circulation (AHA 2024). 2024;150(Suppl 1):A4146655.
Gender disparities in heart failure readmissions and in-hospital mortality among patients with amyloidosis: insights from the National Readmission Database. First
Saha S, Vij A, Varma R, Nandyal S, Kanitsoraphan C, Malhotra S. Poster, ACC Illinois Chapter Meeting, Chicago, IL. 2025.
GLP-1 receptor agonists and cardiovascular outcomes in MASLD: a systematic review and meta-analysis of observational studies. FirstSubmitted
Saha S, Jha A, Thakur A, Philip AM, Santos Argueta HR, Golzar Y. Circulation. 2026.
National & international conference abstracts — co-author (17)
10-year trend in outcomes of acute myocardial infarction hospitalization in patients with type 1 diabetes.
Bello J, Erhus E, Saha S, et al. J Endocr Soc (ENDO 2025). 2025;9(Suppl 1):bvaf149.1035.
New permanent pacemaker implantation risk following TAVR vs SAVR: a meta-analysis of randomized controlled trials in low surgical-risk patients.
Caputi A, Malkani S, Mautong H, et al., Saha S, et al. J Soc Cardiovasc Angiogr Interv (SCAI 2025). 2025;4(5 Suppl):103276.
Gender disparities in heart failure readmissions and in-hospital mortality among patients with amyloidosis: insights from the National Readmission Database.
Varma R, Vij A, Saha S, Nandyal S, Odoi S, Caputi A, Malhotra S. J Nucl Cardiol (ASNC 2025). 2025;50(Suppl):102360.
Atrial arrhythmias and mortality in pulmonary hypertension: systematic review and meta-analysis.
Pena O, Mautong H, Miron JMM, Saha S, et al. Heart Rhythm (HRS 2026). 2026;23(4):S566.
Diagnostic accuracy of late gadolinium enhancement vs invasive angiography for detecting CAD in new-onset heart failure: an updated systematic review and meta-analysis. In press
Pena O, Anweri A, Moreno-Miron JM, et al., Saha S, et al. Journal of Cardiac Failure. 2026.
Comparative efficacy and safety of pulsed-field ablation and conventional thermal ablation in atrial fibrillation: a meta-analysis of randomized trials.
Singla A, Saha S, Mahendru D, et al. J Am Coll Cardiol (ACC 2026). 2026;87(13 Suppl):A87.
Contrasting baseline hemodynamic signatures in cardiogenic shock from acute myocardial infarction and acute heart failure: a meta-analysis.
Saravanabavanandan R, Venugopal D, Saha S, et al. J Am Coll Cardiol (ACC 2025). 2025;85(12 Suppl):2825.
Comparative outcomes of cardiogenic shock in acute myocardial infarction versus acute heart failure: a meta-analysis.
Saravanabavanandan R, Venugopal D, Saha S, et al. Circulation (AHA 2024). 2024;150(Suppl 1):A4143910.
Efficacy of bempedoic acid versus placebo for additional lipid lowering in patients receiving background statin therapy: a meta-analysis of randomized controlled trials.
Singla A, Saha S, Brar A, et al. Circulation (AHA 2025). 2025;152(Suppl 3):A4371829.
Trends of acute myocardial infarction and ventricular arrhythmia–related mortality in the United States, 1999–2020.
Kumar M, Kumar S, Nandyal S, Saha S, et al. Circulation (AHA 2025). 2025;152(Suppl 3):A4371766.
Cardiovascular events in hospitalized patients with malignant neuroendocrine tumors: a nationwide analysis.
Philip A, George LJ, Mautong H, et al., Saha S, et al. Circulation (AHA 2025). 2025;152(Suppl 3):A4368574.
Racial, gender, and comorbidity predictors of cardiovascular mortality in class III obesity: insights from the National Inpatient Sample.
Zuniga AC, Mautong H, Banga A, Philip A, Erhus E, Saha S, et al. Circulation (AHA 2025). 2025;152(Suppl 3):A4369704.
Clinical efficacy of telemedicine vs standard outpatient management for heart failure: a systematic review and meta-analysis.
Syed S, Ochani RK, Hotwani P, et al., Saha S, et al. Circulation (AHA 2025). 2025;152(Suppl 3):A4367189.
Cocaine use, hypertensive emergency, and aortic dissection: a nationwide trend and outcome analysis, 2016–2021.
Philip A, George LJ, Saha S, et al. Hypertension (AHA Hypertension 2025). 2025;82(Suppl 1):FR612.
Elevated pericoronary fat attenuation on coronary CT angiography is associated with major adverse cardiovascular events and improves risk discrimination in type 2 diabetes: a systematic review and meta-analysis. Submitted
Srikrishna D, Moreira Macedo H, Saha S, Papatheodorou N, Sharma D. Circulation. 2026.
Sepsis in Takotsubo cardiomyopathy: association with ventricular arrhythmias, mechanical circulatory support, and mortality. Submitted
Santos Argueta H, Santos Argueta A, Saha S, et al. Circulation. 2026.
Biventricular Takotsubo syndrome following sunitinib initiation: diagnostic and prognostic insights from cardiac magnetic resonance imaging. Submitted
Sabanci R, Saha S, Shrestha P, Gomez J. Circulation. 2026.

Ongoing projects & mentorship

Predischarge TTE parameters as predictors of 30-day readmission in HFpEF
Retrospective cohort; IRB-approved, data collection ongoing. Serves as the mentored MSCI thesis.
PI: Yasmeen Golzar, MD
PET-diagnosed coronary microvascular disease & MACE
Systematic review and meta-analysis; presented at ASNC 2025, manuscript in preparation.
PI: Saurabh Malhotra, MD
Biventricular Takotsubo following sunitinib — case report
Manuscript complete; under review.
PI: Javier Gomez Valencia, MD
National trends in AMI hospitalizations among adults with type 1 diabetes
National Inpatient Sample study (2016–2023); manuscript in progress.
PI: Hafeez Shaka, MD

Journal peer-review service

Multiple peer reviews for Frontiers in Cardiovascular Medicine, Frontiers in Endocrinology, Frontiers in Oncology, and Cureus.

Credentials & Recognition

Licensure, examinations, memberships, and honors

Licensure & certification
  • Nov 2022USMLE Step 1 — passed
  • Jun 2023USMLE Step 2 CK — passed
  • Dec 2023USMLE Step 3 — passed
  • CurrentBLS & ACLS provider certification
  • CurrentIllinois medical license
  • CurrentTamil Nadu Medical Council (India)
Professional memberships
  • American College of Cardiology (ACC)
  • American Heart Association (AHA)
  • American Society of Nuclear Cardiology (ASNC)
  • American College of Physicians (ACP)
  • National Lipid Society (NLS)
Honors & awards
  • 2026Outstanding Abstract Award, ENDO 2026 (Endocrine Society Annual Meeting)
  • 2026Institutional Award for Outstanding Poster Presentation, Cook County Health
  • 2019Gwenda Lewis Prize for Anesthesia, CMC Vellore
  • 2019Institutional grant — international poster presentation, TUFH Conference, Darwin, Australia
  • 2018Full scholarship for medical student exchange, Uppsala University, Sweden (top 10 in class)
  • 2015Rank 1, West Bengal Joint Entrance Examination (WBJEE)
  • 2014KVPY scholarship — Dept. of Science & Technology, Govt. of India
  • 2013NTSE scholarship — NCERT, Govt. of India

Teaching, Leadership & Service

Education, mentorship, and community engagement

Curriculum Committee & Program Representative
Cook County Health · 2024 – present
Contributed to major internal medicine curriculum changes (MICU roster modernization, floor workflow redesign, resident-led didactics) and represented the program in recruitment.
Research Mentorship
Since 2019
Mentored two groups of junior medical students through research projects from question to publication, and guided one student longitudinally through medical school.
UDHAVI COVID-19 Telemedicine Helpline
CMC Vellore · 2021
Junior-most member of a physician-led helpline providing evidence-based telephone consultations to patients in remote regions during pandemic lockdowns, in 4–6 hour daily shifts alongside full-time clinical duties.
‘Cognitio’ Research Symposium & Rural Camps
CMC Vellore · 2015 – 2018
Treasurer (2017) and Organizer-in-charge (2018) of an undergraduate research symposium; volunteered for multiple weeks at rural medical camps in Karnataka and Assam as a medical student.
Languages & interests
Fluent in English, Bengali, Hindi, and Tamil. Lifelong swimmer; chess; Indian classical vocals and harmonium. Research tools: R, SPSS, STATA, RevMan, DistillerSR, Rayyan, LaTeX.